A global pandemic might seem like a crazy time to change chief executives. Vertex shares kept climbing, to an all-time high this week; it was one of the few Massachusetts stocks to rise during the stock market free fall in the first quarter. Of course, he had no idea the coronavirus would upend the world order.

But he laid the groundwork for a gradual transition — he stays on as executive chairman for three years — and built up extra inventories of cystic fibrosis treatments and redundant supply chains that could withstand interruptions. It also said it had more than enough drugs to meet the needs of cystic fibrosis patients. Investors seemed more impressed about the forecast, and less worried about the trials. He was named CEO in Decemberless than a month after rival Gilead reached a deal to buy Pharmasset, a company with no drugs on the market but one treatment that showed promising results for hepatitis C.

This is important because Vertex had just built a billion-dollar franchise around its own hepatitis C treatment, Incivek. It did not take long for Gilead to outmaneuver Vertex with a better drug. ByIncivek was doneand Vertex walked away completely from that business. Leiden was determined to ensure the company would not make the same mistake. While building the cystic fibrosis franchise, Leiden said, the company worked continually to study better treatments.

Its fourth treatment for the disease, Trikafta, won federal approval in October. The drug could help 90 percent of those suffering from cystic fibrosis around the world, making it the most effective treatment on the market. Meanwhile, Vertex is diversifying, with drugs in clinical development to treat five different ailments, in addition to cystic fibrosis.

This enables the company to spend more than 70 percent of its operating expenses on research and development, an unusually high number for a biotech of its size. Going forward, Leiden will focus on government relations and business development.

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Also on his to-do list: getting a new cell and genetic therapy facility in South Boston built and running next year, and helping the company respond to the pandemic right now.

Kewalramani will handle the day-to-day operations as CEO. This will be a full-time chairmanship, although Leiden hopes to pare back his commitments to Vertex over the course of the three-year transition. As part of that group, Leiden helped usher in a new crop of digital health startups, to seed the next generation of leaders in the field; Leiden will take over for current chairman Bob Reynolds on Jan.

Jon Chesto can be reached at jon. Follow him on Twitter jonchesto. Email to a Friend. View Comments.Sure, these numbers are only from a short period of time, but they underscore the resilience of and opportunities for renewable energy.

Brookfield Renewable owns and operates hydroelectric, solar, and wind power generation facilities on four continents. Look for Brookfield Renewable to expand its capacity significantly over the next decade.

Corbus CRBP releases disappointing top-line results from its week phase IIb study of lenabasum in patients with cystic fibrosis. Yahoo Finance.

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Vertex Pharmaceuticals Incorporated (VRTX)

Mid Term. Long Term. Previous Close Volume 1, Market Cap Estimated return represents the projected annual return you might expect after purchasing shares in the company and holding them over the default time horizon of 5 years, based on the EPS growth rate that we have projected. Research that delivers an independent perspective, consistent methodology and actionable insight.

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Day's Range. Beta 5Y Monthly. Earnings Date. Oct 28, - Nov 02, Ex-Dividend Date.As our Chief Patient Officer, what I love about our values is that they put patients at the center of everything we d….

Home Featured. As our Chief Patient Officer, what I love about our values is that …. David Altshuler, M. August 26, At Vertex, we believe the most important medicines are those that have transformative impact for patients. And while drug discovery and development ar…. June 11, At Vertex, our strategy is to invest in scientific innovation to make transformative medicines for serious diseases. We are advancing that strategy wi…. The Vertex Foundation Scholarship helps people with cystic fibrosis CF and their immediate family members pursue two-year, four-year or graduate deg….

We live in a world that relies on data.


Data is used to inform everything from our hiring practices, to our building and lab designs, our clinical dev…. Vertex Foundation.

Partnering with our communities to make the places where we live and work stronger is a priority for the Vertex Foundation, especially during these un….

U.S. FDA Approves Expanded Indication for Our First Cystic Fibrosis Medicine

Commitment to patients. One of the reasons I joined Vertex back in was the fierce passion I felt from every employee to pursue science in the name of transforming lives ….

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The Milken Institute released new essays in their PowerofIdeas series on the unique challenges, opportunities for growth and collaborative responses …. We also know that a respiratory illness can be especially …. STEM Week. I love the work we do at Vertex to get kids excited about science.United States.

This is our corporate page and not a page for our approved or investigational medicines. As a biotechnology company, at times our engagement may seem limited or delayed, but that is because we must adhere to certain ethical, legal, and regulatory standards unique to this industry.

To ensure our communications are consistent with our mission and public obligations, below are our Community Guidelines. They are subject to change at any time, so we encourage you to check back often. Please note that we reserve the right to block users from this page who violate or misuse these Community Guidelines. We will not engage on these topics and comments containing this information may be removed.

Please be respectful of others. Do not use disparaging, discriminatory, harassing, or intimidating language or any content that could encourage or be considered offensive or violate any law.

This content will be removed. Please do not use this page to promote your product, post advertisements, or solicit business. Do not share content that contains confidential, sensitive, or non-public information, or any content that infringes on intellectual property rights or on the privacy or publicity rights of others.

For any questions related to sponsorships, scholarships, employment, or any other solicitation for services, please do not post on the page. All comments containing information about clinical trials that you or someone you know has participated in will be removed from the page. Vertex may contact you directly to follow up regarding your experience with a Vertex product.

Additionally, any personal information that you provide may be processed in internal Vertex databases and sent to regulators. Vertex and the Vertex triangle logo are registered trademarks of Vertex Pharmaceuticals Incorporated. Choose your Region. Americas Custom Icon. Europe Custom Icon.

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Custom Icon. Rest of the World Custom Icon. If you have a medical question related to your condition, please talk to your doctor. Twitter accounts that Vertex follows or is followed by do not indicate an endorsement of the account owner or their products and services Vertex may provide links or references to other sites as part of its Tweets.

However, Vertex claims no responsibility for the content of such other sites and shall not be liable for any damages or injury arising from that content.

Any links to other sites are provided as merely a convenience to the users of this platform Vertex reserves the right to add, remove or modify any content or material posted on the account, discontinue the account, accept or reject those who may wish to follow the account and respond to any questions or comments addressed to the account No other entity other than Vertex and its authorized users may represent the company Vertex and the Vertex triangle logo are registered trademarks of Vertex Pharmaceuticals Incorporated.Vertex has been going from strength to strength recently.

The storied brand was revived three years ago, following four decades of dormancy, and has since garnered quite a following. Having re-launched with the M — a modern take on the Vertex field watch supplied to British soldiers — Vertex has gone on to release a black, DLC-coated version of that same design the MBand then the MP45 monopusher chronograph. Now, the M Series is back, in what we think is an especially attractive incarnation. As you might expect, the Bronze 75 is cased in bronze.

It also lends the watch an attractive, old-school countenance — a quality that the Bronze 75 elaborates across its design. Take the strap, for instance, which is made from vintage brown leather. Or look at the caseback. As with all M Series pieces, however, it has some reassuringly modern features. The movement, for instance, is a robust ETAand the numbers are fashioned from solid Super-LumiNova, making it easy to read in low light.

But if you want one, you'll have to act fast — only pieces are available. Longines re-creates a classic watch made for the French Navy. British GQ.

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Edition Britain Chevron. Facebook Twitter Pinterest. GQ Recommends. By Adrian Hailwood 22 September By Tracey Llewellyn 15 July One of the business pioneers of the Seaport District appears ready to grow in a new corner of the burgeoning neighborhood. Vertex Pharmaceuticals is poised to lease a building under construction in the Raymond L. Flynn Marine Industrial Park, the biotechnology company said this week.

A lease has not been finalized, but Vertex and development firm Related Beal are in advanced talks forsquare feet of space at Innovation Square, a lab and office project Related is building on Tide Street. Earlier this year, the drug maker bought Watertown-based Exonics, which is developing gene therapies for Duchenne muscular dystrophy, and Semma Therapeutics, which is working on medicines for type 1 diabetes.

Vertex also is moving forward in clinical trials of gene editing treatments. Jeffrey Leiden. Vertex looked at sites in Cambridge, Waltham, Watertown, and elsewhere around the region, Leiden said, but settled on the Seaport, where it moved its headquarters and 1, employees from Kendall Square five years ago.

Other than Vertex, many of the larger businesses to initially move to the Seaport were law and accounting firms decamping from downtown, but the neighborhood is increasingly becoming a destination for life sciences firms. Alexion Pharmaceuticals and Ginkgo Bioworks have moved into new space, while Foundation Medicine said it plans to lease nearly all of a story building under construction at Seaport Square. At Innovation Square — a two-phase, ,square-foot project on the eastern edge of the Seaport — Related Beal bet that it could build lab space, and the tenants would come.

There were other factors as well. He acknowledged that transportation in and out of the neighborhood has become a serious challenge since the company moved there, but said he was hopeful that the other big companies in the area will work together to find solutions. We need a better plan. Tim Logan can be reached at tim. Follow him on Twitter at bytimlogan. Email to a Friend. View Comments. Related Beal.The minimum and maximum bets and game rules are all available for each game offered on www. Should Betbull decide to close a Player's account, bets which have already been placed and accepted will not be voided and the Player will be paid any winnings.

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